Oxandrolone – Anavar
Anavar is a mild anabolic steroid and widely used by many athletes and body builders. The chief reason for its use is that the drug can help one gain weight.
One of the main reasons why this drug is very popular among athletes is that it does not get converted into estrogen. This results in less gynecomastia. Some even claim that the water retention is much less with this drug.
Anavar was first introduced in the North American Market nearly 50 years ago. During the early days it was used to treat a variety of infertility disorders, anemias and those ill individuals in hospitals who were wasting away. However, the drug is not widely used in clinical medicine today. Anavar has two major advantages compared to other anabolic steroids. It does not get converted into estrogen and it does not significantly influence the hypothalamic pituitary tract at low doses. What this means is that because it is not broken down to estrogen, males will not develop breast enlargement. Secondly, because it does not affect the hypothalamic pituitary axis, it does not affect the suppression of testosterone. This means that the individual taking Anavar will not have such side effects like loss of libido, impotence or testicular atrophy- features that are commonly seen with other anabolic steroids.
Oxandrin is a both an anabolic steroid and has all the properties of an androgenic drug. The actions of the drug are similar to those seen with testosterone. At low doses the drug has selective anabolic properties, but at high doses, it also has potent androgenic activity. When used at high doses, the drug can influence the hypothalamus and suppress the release of the Gonadotropins and this leads to a decrease in the synthesis of testosterone. Like all other anabolic steroids, Oxandrin also increases the levels of “bad” LDL cholesterol and decreases the levels of “good” HDL cholesterol. Anavar is one of the few anabolic steroids which is not converted to estrogen at low doses.
The drug is rarely used in clinical medicine. In the past decades, it was used to treat individuals with a variety of anemias, weight loss in HIV patients and was once tried out as treatment for osteoporosis. However, the widespread abuse of this drug led Searle in 1989, to cease production of the drug. Today, the drug is made by Savient Pharmaceutical, under the trade name Oxandrin. Today, some physicians do prescribe Oxandrin to treat moribund patients gain weight after trauma, burns or serious infections. Sometimes it is combined with corticosteroids for the treatment of bone pain in cancer patients.